Personal Differences
Before we get into what actually may make one strain more potent than another, we need to address the fact that different strains of cannabis don’t always affect everyone the same way. A strain that makes one person giggly may put someone else to sleep or make them paranoid. And, on top of the genetic factors that influence how an we experience a strain, the specifics of our body chemistry can be altered by diet, stress, and more – for example, the amount of omega-3 fatty acids in your recent diet can have a dramatic effect on your initial endocannabinoid levels. The dose you take and your tolerance will also affect how potent you perceive a strain to be.
What Determines Cannabis Potency
THC is a powerful, prevalent cannabinoid, but it isn’t the only one that has an effect. CBD can counteract some of the racing thoughts and anxiety that THC causes without “killing” the high, which means that users could get higher more comfortably with balanced strains rather than THC-dominant ones. Sadly, we don’t know much more than that when it comes to cannabinoids. There are more than 100 different cannabinoids found in cannabis, and most of them have been largely or completely unstudied. However, it’s likely that the variations in the levels of various cannabinoids from one strain to another plays a significant role in potency. Terpenes are also a factor. These are the compounds that give cannabis (and many other plants) their signature smells. Their effects are subtle on their own, but are magnified when ingested as part of the whole cannabis plant. Different strains have different mixes of terpenes, and some strains have a wider variety of terpenes than others.If you want to learn even more about growing good cannabis, we offer a free 40+ page guide full of images.
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Mike Drouin is the co-founder of Reefertilizer. He’s an experienced craft cannabis grower and a writer of many articles regarding the process. Mike lives on Vancouver Island and enjoys cycling and camping and will sometimes combine the two.


